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Thalidomide-O-C4-NH2 hydrochloride

CAS No. 2376990-29-1

Thalidomide-O-C4-NH2 hydrochloride ( Thalidomide-linker 9; Thalidomide-O-C4-NH2 hydrochloride )

Catalog No. M28663 CAS No. 2376990-29-1

Thalidomide-linker 9 is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Thalidomide-O-C4-NH2 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Thalidomide-linker 9 is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
  • Description
    Thalidomide-linker 9 is a synthesized?E3 ligase ligand-linker conjugate?that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
  • Synonyms
    Thalidomide-linker 9; Thalidomide-O-C4-NH2 hydrochloride
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Cytochrome P450
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2376990-29-1
  • Formula Weight
    381.8
  • Molecular Formula
    C17H20ClN3O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCCCN)=O.[H]Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hoyt SB, et al. Discovery of Benzimidazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys.ACS Med Chem Lett. 2015 Apr 7;6(5):573-8.
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